Abstrait

Saponins and their potential role in diabetes mellitus

Amira Ragab El Barky*, Samy Ali Hussein, AbeerAbd-Elhameed Alm-Eldeen, yehia Ahmed Hafez & Tarek Mostafa Mohamed

Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by an increase in the serum blood glucose levels. DM resulted from defects in insulin secretion, action, or both of them. The chronic hyperglycemia resulted from diabetes can lead to irreversible damage, dysfunction and failure of various organs. Glycosidic compounds namely, saponins, are shown to have potential therapeutic benefits and are theorized as an alternative medication in decreasing serum blood glucose level in patients they suffering from diabetes. This review article aimed to elucidate the antidiabetic activity of saponins as well as showed their merit that makes them ideal for antidiabetic remediation.