Abstrait

Future and experimental therapeutic strategies for allergic rhinitis and asthma

Giovanni Passalacqua

The rapid progress in our understanding of basic immunology has recently enabled the identifcation of many possible therapeutic targets for the treatment of respiratory allergy and allergic inflammation. As a result, new approaches have been proposed and tested in rhinitis and asthma, including new drugs and mediator antagonists, monoclonal antibodies and immunosuppressant agents. Only a small number of these approaches have become a reality, however, all of them have provided us with the opportunity to improve our knowledge in the field. We will review herein some of the experimental approaches used in humans in relation to the pathogenic aspects of allergic inflammation.